Heparanase levels are elevated in the urine and plasma of type 2 diabetes patients and associate with blood glucose levels.

Heparanase is an endoglycosidase that specifically cleaves heparan sulfate side chains of heparan sulfate proteoglycans. Utilizing an ELISA method capable of detection and quantification of heparanase, we examined heparanase levels in the plasma and urine of a cohort of 29 patients diagnosed with ty...

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Bibliographic Details
Main Authors: Itay Shafat, Neta Ilan, Samih Zoabi, Israel Vlodavsky, Farid Nakhoul
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-02-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3043098?pdf=render