Basal Serum Thyroxine Level should Guide Initial Thyroxine Replacement Dose in Neonates with Congenital Hypothyroidism

Basal Serum Thyroxine Level should Guide Initial Thyroxine Replacement Dose in Neonates with Congenital Hypothyroidism

Objective:Initial high-dose sodium levothyroxine (Na-LT4) (10-15 μg/kg/day) replacement for primary congenital hypothyroidism (CH) is recommended in guidelines. However, high-dose Na-LT4 risks iatrogenic hyperthyroidism. The aim of this study was to investigate the normalizing effect of varying init...

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Bibliographic Details
Main Authors: Ceren Günbey, Alev Özön, E. Nazlı Gönç, Ayfer Alikaşifoğlu, Sevilay Karahan, Nurgün Kandemir
Format: Article
Language:English
Published: Galenos Yayincilik 2021-09-01
Series:JCRPE
Subjects:
newborn screening
children
congenital hypothyroidism
na-l thyroxine
dose
Online Access: http://www.jcrpe.org/archives/archive-detail/article-preview/basal-serum-thyroxine-level-should-guide-nitial-th/42983

Internet

http://www.jcrpe.org/archives/archive-detail/article-preview/basal-serum-thyroxine-level-should-guide-nitial-th/42983

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