Loganin Inhibits Angiotensin II–Induced Cardiac Hypertrophy Through the JAK2/STAT3 and NF-κB Signaling Pathways

Loganin Inhibits Angiotensin II–Induced Cardiac Hypertrophy Through the JAK2/STAT3 and NF-κB Signaling Pathways

Loganin is an iridoid glycoside extracted from Cornus officinalis, which is a traditional oriental medicine, and many biological properties of loganin have been reported. Nevertheless, it is not clear whether loganin has therapeutic effect on cardiovascular diseases. Hence, the aim of the present st...

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Bibliographic Details
Main Authors: Jia-jia Xu, Run-jing Li, Zheng-hao Zhang, Cui Yang, Shi-xiao Liu, Yan-ling Li, Min-wei Chen, Wei-wei Wang, Gong-ye Zhang, Gang Song, Zheng-rong Huang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Pharmacology
Subjects:
loganin
angiotensin II
cardiac hypertrophy
cardiac fibrosis
inflammation
JAK2/STAT3
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.678886/full

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https://www.frontiersin.org/articles/10.3389/fphar.2021.678886/full

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