Proteasome inhibitors: new class of antitumor agents
The ubiquitin-proteasome pathway is the principal pathway for intracellular protein degradation1,2 (Fig 1). This pathway selectively degrades an extensive number of short-lived regulatory proteins involved in the control of normal cellular processes. In order to be degraded, proteins targeted by the...
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Format: | Article |
Language: | English |
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Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina
2003-11-01
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Series: | Bosnian Journal of Basic Medical Sciences |
Online Access: | http://www.bjbms.org/ojs/index.php/bjbms/article/view/3484 |