Proteasome inhibitors: new class of antitumor agents

The ubiquitin-proteasome pathway is the principal pathway for intracellular protein degradation1,2 (Fig 1). This pathway selectively degrades an extensive number of short-lived regulatory proteins involved in the control of normal cellular processes. In order to be degraded, proteins targeted by the...

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Bibliographic Details
Main Author: Gordan Srkalović
Format: Article
Language:English
Published: Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina 2003-11-01
Series:Bosnian Journal of Basic Medical Sciences
Online Access:http://www.bjbms.org/ojs/index.php/bjbms/article/view/3484