Nanoalginates via Inverse-Micelle Synthesis: Doxorubicin-Encapsulation and Breast Cancer Cytotoxicity

Abstract Crosslinked-biopolymer nanoparticles provide a convenient platform for therapeutic encapsulation and delivery. Here, we present a robust inverse-micelle process to load water-soluble drugs into a calcium-crosslinked alginate matrix. The utility of the resulting nanoalginate (NALG) carriers...

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Bibliographic Details
Main Authors: Justin G. Rosch, Anna L. Brown, Allison N. DuRoss, Erin L. DuRoss, Gaurav Sahay, Conroy Sun
Format: Article
Language:English
Published: SpringerOpen 2018-11-01
Series:Nanoscale Research Letters
Subjects:
Online Access:http://link.springer.com/article/10.1186/s11671-018-2748-2