A spectrum of exercise training reduces soluble Aβ in a dose-dependent manner in a mouse model of Alzheimer's disease

A spectrum of exercise training reduces soluble Aβ in a dose-dependent manner in a mouse model of Alzheimer's disease

Physical activity has long been hypothesized to influence the risk and pathology of Alzheimer's disease. However, the amount of physical activity necessary for these benefits is unclear. We examined the effects of three months of low and high intensity exercise training on soluble Aβ40 and Aβ42...

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Bibliographic Details
Main Authors: Kaitlin M. Moore, Renee E. Girens, Sara K. Larson, Maria R. Jones, Jessica L. Restivo, David M. Holtzman, John R. Cirrito, Carla M. Yuede, Scott D. Zimmerman, Benjamin F. Timson
Format: Article
Language:English
Published: Elsevier 2016-01-01
Series:Neurobiology of Disease
Subjects:
Alzheimer's disease
Physical activity
Exercise training
Amyloid-β
Amyloid-β clearance proteins
Heat shock protein 70
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996115300838

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http://www.sciencedirect.com/science/article/pii/S0969996115300838

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