TATN-1 mutations reveal a novel role for tyrosine as a metabolic signal that influences developmental decisions and longevity in Caenorhabditis elegans.

TATN-1 mutations reveal a novel role for tyrosine as a metabolic signal that influences developmental decisions and longevity in Caenorhabditis elegans.

Recent work has identified changes in the metabolism of the aromatic amino acid tyrosine as a risk factor for diabetes and a contributor to the development of liver cancer. While these findings could suggest a role for tyrosine as a direct regulator of the behavior of cells and tissues, evidence for...

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Bibliographic Details
Main Authors: Annabel A Ferguson, Sudipa Roy, Kaitlyn N Kormanik, Yongsoon Kim, Kathleen J Dumas, Vladimir B Ritov, Dietrich Matern, Patrick J Hu, Alfred L Fisher
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3868569?pdf=render

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http://europepmc.org/articles/PMC3868569?pdf=render

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