Permeability of Novel Chitosan-g-Poly(Methyl Methacrylate) Amphiphilic Nanoparticles in a Model of Small Intestine In Vitro

Permeability of Novel Chitosan-g-Poly(Methyl Methacrylate) Amphiphilic Nanoparticles in a Model of Small Intestine In Vitro

Engineering of drug nanocarriers combining fine-tuned mucoadhesive/mucopenetrating properties is currently being investigated to ensure more efficient mucosal drug delivery. Aiming to improve the transmucosal delivery of hydrophobic drugs, we designed a novel nanogel produced by the self-assembly of...

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Bibliographic Details
Main Authors:	Imrit Noi, Inbar Schlachet, Murali Kumarasamy, Alejandro Sosnik
Format:	Article
Language:	English
Published:	MDPI AG 2018-04-01
Series:	Polymers
Subjects:	Chitosan-g-PMMA amphiphilic nanoparticles thiolated polymers mucoadhesion mucosal drug delivery Caco-2 and HT29-MTX cell lines apparent permeability in vitro
Online Access:	http://www.mdpi.com/2073-4360/10/5/478

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