Detection of N-RAS gene mutations in codons 12,13 and 61 in patients with pediatric acute lymphoblastic leukemia

Background: Acute leukemia is the prevalent malignancy in pediatrics. One of the most important causing factors of acute lymphoblastic leukemia is mutations of proto oncogenes and their chang in to oncogenes. Activation of N-RAS proto-oncogene due to point mutations plays a major role in ALL maligna...

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Bibliographic Details
Main Authors: Mahin Behzadifard, Yosof Mortazavi, Sadegh Rezapour, Ali akbar Pourfatholah, Saeed Kavyani, Mansoure Haghighi, Samane Behzadifard
Format: Article
Language:fas
Published: Lorestan University of Medical Science 2011-12-01
Series:Yafteh
Subjects:
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Online Access:http://yafte.lums.ac.ir/browse.php?a_code=A-10-1-14&slc_lang=en&sid=1