A Paradigmatic Interplay between Human Cytomegalovirus and Host Immune System: Possible Involvement of Viral Antigen-Driven CD8+ T Cell Responses in Systemic Sclerosis

A Paradigmatic Interplay between Human Cytomegalovirus and Host Immune System: Possible Involvement of Viral Antigen-Driven CD8+ T Cell Responses in Systemic Sclerosis

Human cytomegalovirus (HCMV) is a highly prevalent opportunistic agent in the world population, which persists as a latent virus after a primary infection. Besides the well-established role of this agent causing severe diseases in immunocompromised individuals, more recently, HCMV has been evoked as...

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Bibliographic Details
Main Authors: Maria-Cristina Arcangeletti, Clara Maccari, Rosanna Vescovini, Riccardo Volpi, Dilia Giuggioli, Gianluca Sighinolfi, Flora De Conto, Carlo Chezzi, Adriana Calderaro, Clodoveo Ferri
Format: Article
Language:English
Published: MDPI AG 2018-09-01
Series:Viruses
Subjects:
human cytomegalovirus
virus-host interactions
systemic sclerosis
antigen-driven T cell responses
disease duration
modified Rodnan skin score
Online Access:http://www.mdpi.com/1999-4915/10/9/508

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http://www.mdpi.com/1999-4915/10/9/508

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