Inhibition of autophagy enhances the anticancer effect of enzalutamide on bladder cancer

Inhibition of autophagy enhances the anticancer effect of enzalutamide on bladder cancer

Background: Emerging preclinical evidence suggests a critical role for androgen-mediated androgen receptor (AR) signaling in bladder cancer progression. However, researchers have not determined whether autophagy modulates the efficacy of an enzalutamide (ENZ) treatment in subjects with advanced blad...

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Bibliographic Details
Main Authors: Yongjun Quan, Hongen Lei, Wasilijiang Wahafu, Yuexin Liu, Hao Ping, Xiaodong Zhang
Format: Article
Language:English
Published: Elsevier 2019-12-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Bladder cancer
Enzalutamide
Autophagy inhibitor
Androgen receptor
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332219331105

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http://www.sciencedirect.com/science/article/pii/S0753332219331105

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