Decrease of Klotho in the Kidney of Streptozotocin-Induced Diabetic Rats

The klotho gene is expressed in a limited number of tissues, most notably in distal convoluted tubules in the kidney and choroid plexus in the brain. A previous study suggested that Klotho increases resistance to oxidative stress. However, changes of Klotho expression in high glucose-induced oxidati...

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Bibliographic Details
Main Authors: Meng-Fu Cheng, Li-Jen Chen, Juei-Tang Cheng
Format: Article
Language:English
Published: Hindawi Limited 2010-01-01
Series:Journal of Biomedicine and Biotechnology
Online Access:http://dx.doi.org/10.1155/2010/513853