Male germ cell-specific RNA binding protein RBMY: a new oncogene explaining male predominance in liver cancer.

Male gender is a risk factor for the development of hepatocellular carcinoma (HCC) but the mechanisms are not fully understood. The RNA binding motif gene on the Y chromosome (RBMY), encoding a male germ cell-specific RNA splicing regulator during spermatogenesis, is aberrantly activated in human ma...

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Main Authors: Daw-Jen Tsuei, Po-Huang Lee, Hsiao-Yu Peng, Hsiao-Ling Lu, De-Shiuan Su, Yung-Ming Jeng, Hey-Chi Hsu, Shu-Hao Hsu, Jia-Feng Wu, Yen-Hsuan Ni, Mei-Hwei Chang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3208560?pdf=render