Inhibition of autophagy promoted high glucose/ROS-mediated apoptosis in ADSCs

Abstract Background Increased apoptosis in adipose tissue-derived stem cells (ADSCs) limits their application in treating diabetes complications. Autophagy is a molecular process that allows cells to degrade and recover damaged macromolecules, and closely interacts with apoptosis. The aim of the pre...

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Bibliographic Details
Main Authors: Qiang Li, Yating Yin, Yuqing Zheng, Feifei Chen, Peisheng Jin
Format: Article
Language:English
Published: BMC 2018-10-01
Series:Stem Cell Research & Therapy
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13287-018-1029-4