Tumor Heterogeneity, Single-Cell Sequencing, and Drug Resistance
Tumor heterogeneity has been compared with Darwinian evolution and survival of the fittest. The evolutionary ecosystem of tumors consisting of heterogeneous tumor cell populations represents a considerable challenge to tumor therapy, since all genetically and phenotypically different subpopulations...
Main Authors: | Felix Schmidt, Thomas Efferth |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2016-06-01
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Series: | Pharmaceuticals |
Subjects: | |
Online Access: | http://www.mdpi.com/1424-8247/9/2/33 |
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