Effects of osmolytes and macromolecular crowders on stable GAAA tetraloops and their preference for a CG closing base pair
Osmolytes and macromolecular crowders have the potential to influence the stability of secondary structure motifs and alter preferences for conserved nucleic acid sequences in vivo. To further understand the cellular function of RNA we observed the effects of a model osmolyte, polyethylene glycol (P...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
PeerJ Inc.
2018-02-01
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Series: | PeerJ |
Subjects: | |
Online Access: | https://peerj.com/articles/4236.pdf |