Intracerebroventricular Coadministration of Protoxin-II and Trace Elements in Rats Enhances the Analgesic Effect of the 1.7 Voltage-Gate Sodium Channel Blocker

Pain continues to be a global unmet medical need, and the current recommendations for its management require a constant exploration of new drugs that target multiple pain mechanisms, with an improved safety profile and increased treatment adherence. Currently, the enriched distribution and localizat...

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Main Authors: Gabriela-Dumitrita Stanciu, Andrei Luca, Aurelia Marza, Teodora Alexa-Stratulat, Ionut Tudorancea, Walther Bild, Elena Rezus, Ciprian Rezus, Bogdan I. Tamba
Format: Article
Language:English
Published: Hindawi Limited 2019-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2019/8057803