Taking advantage of a high-throughput flow cytometer for the implementation of an ADCC assay for regulatory compliance

Taking advantage of a high-throughput flow cytometer for the implementation of an ADCC assay for regulatory compliance

Technological advances allowed the development of high-throughput instruments such as IntelliCyt iQue Screener PLUS®. Here, we took advantage of this technology to transfer a previously validated cytotoxicity assay. The evaluated parameters were cell permeability, caspase activation and phosphatidyl...

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Bibliographic Details
Main Authors: Rosa Camacho-Sandoval, Alexis Jiménez-Uribe, Alejandra V. Tenorio-Calvo, Carlos A. López-Morales, Leslie Muñoz-García, Alejandra Montes-Luna, Héctor Leonardo García-Xolalpa, Marco Velasco-Velázquez, Lenin Pavón, Sonia Mayra Pérez-Tapia, Emilio Medina-Rivero
Format: Article
Language:English
Published: Elsevier 2020-06-01
Series:Biotechnology Reports
Subjects:
ADCC
High-throughput flow cytometry
Validation bioassay
Online Access:http://www.sciencedirect.com/science/article/pii/S2215017X19305181

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http://www.sciencedirect.com/science/article/pii/S2215017X19305181

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