A constitutional translocation t(1;17)(p36.2;q11.2) in a neuroblastoma patient disrupts the human NBPF1 and ACCN1 genes.

A constitutional translocation t(1;17)(p36.2;q11.2) in a neuroblastoma patient disrupts the human NBPF1 and ACCN1 genes.

The human 1p36 region is deleted in many different types of tumors, and so it probably harbors one or more tumor suppressor genes. In a Belgian neuroblastoma patient, a constitutional balanced translocation t(1;17)(p36.2;q11.2) may have led to the development of the tumor by disrupting or activating...

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Bibliographic Details
Main Authors: Karl Vandepoele, Vanessa Andries, Nadine Van Roy, Katrien Staes, Jo Vandesompele, Geneviève Laureys, Els De Smet, Geert Berx, Frank Speleman, Frans van Roy
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-05-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/18493581/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/18493581/?tool=EBI

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