Identification of a Broadly Cross-Reactive Epitope in the Inner Shell of the Norovirus Capsid.

Noroviruses are major pathogens associated with acute gastroenteritis. They are diverse viruses, with at least six genogroups (GI-GVI) and multiple genotypes defined by differences in the major capsid protein, VP1. This diversity has challenged the development of broadly cross-reactive vaccines as w...

Full description

Bibliographic Details
Main Authors: Gabriel I Parra, Jolynn Azure, Renate Fischer, Karin Bok, Carlos Sandoval-Jaime, Stanislav V Sosnovtsev, Peter Sander, Kim Y Green
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3689733?pdf=render