GU81, a VEGFR2 antagonist peptoid, enhances the anti-tumor activity of doxorubicin in the murine MMTV-PyMT transgenic model of breast cancer

<p>Abstract</p> <p>Background</p> <p>Vascular endothelial growth factor (VEGF) is a primary stimulant of angiogenesis under physiological and pathological conditions. Anti-VEGF therapy is a clinically proven strategy for the treatment of a variety of cancers including c...

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Bibliographic Details
Main Authors: Roland Christina L, Udugamasooriya D Gomika, Lynn Kristi D, Castrillon Diego H, Kodadek Thomas J, Brekken Rolf A
Format: Article
Language:English
Published: BMC 2010-07-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/10/397