Highly prevalent Russian HIV-1 V3-loop sequence variants are susceptible to maraviroc
Introduction Maraviroc inhibits CCR5-tropic HIV-1 across different subtypes in vitro and has demonstrated efficacy in clinical trials. V3-loop amino acid variants observed in individual maraviroc-resistant viruses have not been found to be predictive of reduced susceptibility. Sequence-database sear...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2021-06-01
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| Series: | Antiviral Chemistry & Chemotherapy |
| Online Access: | https://doi.org/10.1177/20402066211025156 |