Downregulation of Filamin a Expression in the Aorta Is Correlated With Aortic Dissection

Downregulation of Filamin a Expression in the Aorta Is Correlated With Aortic Dissection

Filamins (FLNs) are actin cross-linking proteins, and as scaffolding proteins, FLNs are closely associated with the stabilization of the cytoskeleton. Nevertheless, the biological importance of FLNs in aortic dissection (AD) has not been well-elucidated. In this study, we first reanalyzed datasets d...

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Bibliographic Details
Main Authors: Yue Chen, Xiang Wei, Zihao Zhang, Yi He, Bo Huo, Xian Guo, Xin Feng, Ze-Min Fang, Ding-Sheng Jiang, Xue-Hai Zhu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
aortic dissection
FLNA
filamins
FOS/JUN
AP-1
bioinformatics
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2021.690846/full

Internet

https://www.frontiersin.org/articles/10.3389/fcvm.2021.690846/full

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