Increased placental mitochondrial fusion in gestational diabetes mellitus: an adaptive mechanism to optimize feto-placental metabolic homeostasis?

IntroductionGestational diabetes mellitus (GDM), a common pregnancy disorder, increases the risk of fetal overgrowth and later metabolic morbidity in the offspring. The placenta likely mediates these sequelae, but the exact mechanisms remain elusive. Mitochondrial dynamics refers to the joining and...

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Bibliographic Details
Main Authors: Joelcio Abbade, Miira Marjuska Klemetti, Abby Farrell, Leonardo Ermini, Taylor Gillmore, Julien Sallais, Andrea Tagliaferro, Martin Post, Isabella Caniggia
Format: Article
Language:English
Published: BMJ Publishing Group 2020-04-01
Series:BMJ Open Diabetes Research & Care
Online Access:https://drc.bmj.com/content/8/1/e000923.full