FRET-based Visualization of PDGF Receptor Activation at Membrane Microdomains

Abstract Platelet-derived growth factor receptor (PDGFR) senses extracellular growth factors and transfer the signals inside the cells regulating cell proliferation, migration and survival. It has been controversial at which membrane microdomains PDGFRs reside and how they control such diverse intra...

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Bibliographic Details
Main Authors: Jihye Seong, Min Huang, Kyoung Mi Sim, Hyunbin Kim, Yingxiao Wang
Format: Article
Language:English
Published: Nature Publishing Group 2017-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-01789-y