Activity of mevalonate pathway inhibitors against breast and ovarian cancers in the ATP-based tumour chemosensitivity assay

<p>Abstract</p> <p>Previous data suggest that lipophilic statins such as fluvastatin and N-bisphosphonates such as zoledronic acid, both inhibitors of the mevalonate metabolic pathway, have anti-cancer effects <it>in vitro </it>and in patients. We have examined the effe...

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Bibliographic Details
Main Authors: Dexel Susanne, Reichelt Ralf, Fernando Augusta, Glaysher Sharon, Kurbacher Christian M, Knight Louise A, Reinhold Uwe, Cree Ian A
Format: Article
Language:English
Published: BMC 2009-01-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/9/38