A GBP 130 derived peptide from Plasmodium falciparum binds to human erythrocytes and inhibits merozoite invasion in vitro

A GBP 130 derived peptide from Plasmodium falciparum binds to human erythrocytes and inhibits merozoite invasion in vitro

The malarial GBP 130 protein binds weakly to intact human erythrocytes; the binding sites seem to be located in the repeat region and this region's antibodies block the merozoite invasion. A peptide from this region (residues from 701 to 720) which binds to human erythrocytes was identified. Th...

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Bibliographic Details
Main Authors: Jorge E Suarez, Mauricio Urquiza, Hernando Curtidor, Luis E Rodriguez, Marisol Ocampo, Elizabeth Torres, Fanny Guzman, Manuel Elkin Patarroyo
Format: Article
Language:English
Published: Instituto Oswaldo Cruz, Ministério da Saúde 2000-08-01
Series:Memórias do Instituto Oswaldo Cruz.
Subjects:
Plasmodium falciparum
GBP 130
binding assay
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762000000400009

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762000000400009

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