Matrine inhibits the growth of natural killer/T-cell lymphoma cells by modulating CaMKIIγ-c-Myc signaling pathway

Matrine inhibits the growth of natural killer/T-cell lymphoma cells by modulating CaMKIIγ-c-Myc signaling pathway

Abstract Background C-Myc overexpression is associated with poor prognosis and aggressive progression of natural killer/T-cell lymphoma (NKTCL). Matrine, a main alkaloid of the traditional Chinese herb Sophora flavescens Ait, has been shown to inhibit cellular proliferation and induce apoptosis of v...

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Bibliographic Details
Main Authors: Jianyou Gu, Yu Zhang, Xiao Wang, Jingjing Xiang, Shu Deng, Dijiong Wu, Junfa Chen, Lihong Yu, Yan Zhou, Yaokun Wang, Jianping Shen
Format: Article
Language:English
Published: BMC 2020-07-01
Series:BMC Complementary Medicine and Therapies
Subjects:
Matrine
NK92 cell
NK/T-cell lymphoma
C-Myc
CaMKIIγ
LMP1
Online Access:http://link.springer.com/article/10.1186/s12906-020-03006-2

Internet

http://link.springer.com/article/10.1186/s12906-020-03006-2

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