Carprofen Permeation Test through Porcine Ex Vivo Mucous Membranes and Ophthalmic Tissues for Tolerability Assessments: Validation and Histological Study

Carprofen Permeation Test through Porcine Ex Vivo Mucous Membranes and Ophthalmic Tissues for Tolerability Assessments: Validation and Histological Study

Carprofen (CP), a non-steroidal anti-inflammatory drug (NSAID), is profusely used in veterinary medicine for its analgesic and anti-inflammatory activity. Some undesirable effects are associated with its systemic administration. Alternative local routes are especially useful to facilitate its admini...

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Bibliographic Details
Main Authors: Lidia Gómez-Segura, Alexander Parra, Ana C. Calpena, Álvaro Gimeno, Antonio Boix-Montañes
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Veterinary Sciences
Subjects:
carprofen
HPLC
permeation test
histological integrity
mucous tolerability
ophthalmic tolerability
Online Access:https://www.mdpi.com/2306-7381/7/4/152

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https://www.mdpi.com/2306-7381/7/4/152

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