Recombinant herpesvirus glycoprotein G improves the protective immune response to Helicobacter pylori vaccination in a mouse model of disease.

Alphaherpesviruses, which have co-evolved with their hosts for more than 200 million years, evade and subvert host immune responses, in part, by expression of immuno-modulatory molecules. Alphaherpesviruses express a single, broadly conserved chemokine decoy receptor, glycoprotein G (gG), which can...

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Bibliographic Details
Main Authors: Louise Baker, Andre M L Chitas, Carol A Hartley, Mauricio J C Coppo, Paola K Vaz, Andrew Stent, James R Gilkerson, Joanne M Devlin, Alison L Every
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24794215/?tool=EBI