HIV Silencing and Inducibility Are Heterogeneous and Are Affected by Factors Intrinsic to the Virus

A reservoir of infected cells in which the HIV genome is transcriptionally silent is acknowledged to be the principal barrier to eradicating the virus from an infected person. A number of cellular processes are implicated in this silencing; however, the viral factors that may contribute remain under...

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Bibliographic Details
Main Authors: Nicholas J. Norton, Hoi Ping Mok, Fatima Sharif, Jack C. Hirst, Andrew M. L. Lever
Format: Article
Language:English
Published: American Society for Microbiology 2019-06-01
Series:mBio
Subjects:
HIV
Online Access:https://doi.org/10.1128/mBio.00188-19