H1 Antihistamines: Current Status and Future Directions

In this review, we compare and contrast the clinical pharmacology, efficacy, and safety of first-generation H1 antihistamines and second-generation H1 antihistamines. First-generation H1 antihistamines cross the blood-brain barrier, and in usual doses, they potentially cause sedation and impair cogn...

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Bibliographic Details
Main Authors: F. Estelle R. Simon, Keith J. Simons
Format: Article
Language:English
Published: Elsevier 2008-01-01
Series:World Allergy Organization Journal
Online Access:http://www.sciencedirect.com/science/article/pii/S1939455119305915