Extracellular matrix stiffness cues junctional remodeling for 3D tissue elongation

The extracellular matrix can shape developing organs, but how external forces direct intercellular morphogenesis is unclear. Here, the authors use 3D imaging to show that elongation of the Drosophila egg chamber involves polarized cell reorientation signalled by changes in stiffness of the surroundi...

Full description

Bibliographic Details
Main Authors: Dong-Yuan Chen, Justin Crest, Sebastian J. Streichan, David Bilder
Format: Article
Language:English
Published: Nature Publishing Group 2019-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-10874-x