Tiagabine improves hippocampal long-term depression in rat pups subjected to prenatal inflammation.

Maternal inflammation during pregnancy is associated with the later development of cognitive and behavioral impairment in the offspring, reminiscent of the traits of schizophrenia or autism spectrum disorders. Hippocampal long-term potentiation and long-term depression of glutamatergic synapses are...

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Bibliographic Details
Main Authors: Aline Rideau Batista Novais, Nadine Crouzin, Mélanie Cavalier, Mathilde Boubal, Janique Guiramand, Catherine Cohen-Solal, Marie-Céleste de Jesus Ferreira, Gilles Cambonie, Michel Vignes, Gérard Barbanel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/25184226/?tool=EBI