The effects of contig length and depth on the estimation of SNP frequencies, and the relative abundance of SNPs in protein-coding and non-coding transcripts of tiger salamanders (<it>Ambystoma tigrinum</it>)
<p>Abstract</p> <p>Background</p> <p>Next-generation sequencing methods have contributed to rapid progress in the fields of genomics and population genetics. Using this high-throughput and cost-effective technology, a number of studies have estimated single nucleotide p...
Main Authors: | , |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2012-06-01
|
Series: | BMC Genomics |
Subjects: | |
Online Access: | http://www.biomedcentral.com/1471-2164/13/259 |