The effects of contig length and depth on the estimation of SNP frequencies, and the relative abundance of SNPs in protein-coding and non-coding transcripts of tiger salamanders (<it>Ambystoma tigrinum</it>)

<p>Abstract</p> <p>Background</p> <p>Next-generation sequencing methods have contributed to rapid progress in the fields of genomics and population genetics. Using this high-throughput and cost-effective technology, a number of studies have estimated single nucleotide p...

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Bibliographic Details
Main Authors: Eo Soo, DeWoody J
Format: Article
Language:English
Published: BMC 2012-06-01
Series:BMC Genomics
Subjects:
Online Access:http://www.biomedcentral.com/1471-2164/13/259