Efficacy of PD-1 & PD-L1 inhibitors in older adults: a meta-analysis

Abstract Background Immune checkpoint inhibitors targeting PD-1/PD-L1 pathway demonstrated promising activities in variety of malignancies, however little is known regarding their efficacy in adults aged ≥65 years. Methods We conducted a systematic review and a study-level meta-analysis to explore e...

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Bibliographic Details
Main Authors: Rawad Elias, Anita Giobbie-Hurder, Nadine Jackson McCleary, Patrick Ott, F. Stephen Hodi, Osama Rahma
Format: Article
Language:English
Published: BMJ Publishing Group 2018-04-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:http://link.springer.com/article/10.1186/s40425-018-0336-8