Soyasaponins can blunt inflammation by inhibiting the reactive oxygen species-mediated activation of PI3K/Akt/NF-kB pathway.

We and others have recently shown that soyasaponins abundant in soybeans can decrease inflammation by suppressing the nuclear factor kappa B (NF-kB)-mediated inflammation. However, the exact molecular mechanisms by which soyasaponins inhibit the NF-kB pathway have not been established. In this study...

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Bibliographic Details
Main Authors: Longying Zha, Jiading Chen, Suxia Sun, Limei Mao, Xinwei Chu, Hong Deng, Junwei Cai, Xuefeng Li, Zhenqi Liu, Wenhong Cao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4169425?pdf=render