Radiolabeling of Human Serum Albumin With Terbium-161 Using Mild Conditions and Evaluation of in vivo Stability

Radiolabeling of Human Serum Albumin With Terbium-161 Using Mild Conditions and Evaluation of in vivo Stability

Targeted radionuclide therapy (TRNT) is a promising approach for cancer therapy. Terbium has four medically interesting isotopes (149Tb, 152Tb, 155Tb and 161Tb) which span the entire radiopharmaceutical space (TRNT, PET and SPECT imaging). Since the same element is used, accessing the various diagno...

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Bibliographic Details
Main Authors: Irwin Cassells, Stephen Ahenkorah, Andrew R. Burgoyne, Michiel Van de Voorde, Christophe M. Deroose, Thomas Cardinaels, Guy Bormans, Maarten Ooms, Frederik Cleeren
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Medicine
Subjects:
terbium-161
radiopharmaceutical
radiolabeling
TRNT
bio-conjugation
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2021.675122/full

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https://www.frontiersin.org/articles/10.3389/fmed.2021.675122/full

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