Phospholipase A<sub>2</sub> Drives Tumorigenesis and Cancer Aggressiveness through Its Interaction with Annexin A1

Phospholipase A<sub>2</sub> Drives Tumorigenesis and Cancer Aggressiveness through Its Interaction with Annexin A1

Phospholipids are suggested to drive tumorigenesis through their essential role in inflammation. Phospholipase A<sub>2</sub> (PLA<sub>2</sub>) is a phospholipid metabolizing enzyme that releases free fatty acids, mostly arachidonic acid, and lysophospholipids, which contribut...

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Bibliographic Details
Main Authors: Lara Vecchi, Thaise Gonçalves Araújo, Fernanda Van Petten de Vasconcelos Azevedo, Sara Teixeria Soares Mota, Veridiana de Melo Rodrigues Ávila, Matheus Alves Ribeiro, Luiz Ricardo Goulart
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Cells
Subjects:
lipid metabolism
phospholipase A<sub>2</sub>
Annexin A1
tumorigenesis
tumor microenvironment
cancer aggressiveness
Online Access:https://www.mdpi.com/2073-4409/10/6/1472

Internet

https://www.mdpi.com/2073-4409/10/6/1472

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