Iron elevates mesenchymal and metastatic biomarkers in HepG2 cells

Abstract Liver iron excess is observed in several chronic liver diseases and is associated with the development of hepatocellular carcinoma (HCC). However, apart from oxidative stress, other cellular mechanisms by which excess iron may mediate/increase HCC predisposition/progression are not known. H...

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Bibliographic Details
Main Authors: Kosha J. Mehta, Paul A. Sharp
Format: Article
Language:English
Published: Nature Publishing Group 2020-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-78348-5