Changes in hepatic gene expression upon oral administration of taurine-conjugated ursodeoxycholic acid in ob/ob mice.

Changes in hepatic gene expression upon oral administration of taurine-conjugated ursodeoxycholic acid in ob/ob mice.

Nonalcoholic fatty liver disease (NAFLD) is highly prevalent and associated with considerable morbidities. Unfortunately, there is no currently available drug established to treat NAFLD. It was recently reported that intraperitoneal administration of taurine-conjugated ursodeoxycholic acid (TUDCA) i...

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Bibliographic Details
Main Authors: Jae-Seong Yang, Jin Taek Kim, Jouhyun Jeon, Ho Sun Park, Gyeong Hoon Kang, Kyong Soo Park, Hong Kyu Lee, Sanguk Kim, Young Min Cho
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2974643?pdf=render

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http://europepmc.org/articles/PMC2974643?pdf=render

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