miR-200c Accelerates Hepatic Stellate Cell-Induced Liver Fibrosis via Targeting the FOG2/PI3K Pathway

Background. Although expression of miR-200s is aberrant in liver fibrosis, its role in liver fibrogenesis still remains unknown. Here, we investigated the role of miR-200c in the activation of human hepatic stellate cells (HSCs) and induction of liver fibrosis. Methods. We engineered human HSCs (LX2...

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Bibliographic Details
Main Authors: Tengfei Ma, Xiuqin Cai, Zifeng Wang, Li Huang, Chang Wang, Songshan Jiang, Yunpeng Hua, Quentin Liu
Format: Article
Language:English
Published: Hindawi Limited 2017-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2017/2670658