Integrating genetic and network analysis to characterize genes related to mouse weight.

Systems biology approaches that are based on the genetics of gene expression have been fruitful in identifying genetic regulatory loci related to complex traits. We use microarray and genetic marker data from an F2 mouse intercross to examine the large-scale organization of the gene co-expression ne...

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Bibliographic Details
Main Authors: Anatole Ghazalpour, Sudheer Doss, Bin Zhang, Susanna Wang, Christopher Plaisier, Ruth Castellanos, Alec Brozell, Eric E Schadt, Thomas A Drake, Aldons J Lusis, Steve Horvath
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2006-08-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC1550283?pdf=render