Enhancement of the Therapeutic Capacity of Mesenchymal Stem Cells by Genetic Modification: A Systematic Review

Enhancement of the Therapeutic Capacity of Mesenchymal Stem Cells by Genetic Modification: A Systematic Review

BackgroundThe therapeutic capacity of mesenchymal stem cells (also known as mesenchymal stromal cells/MSCs) depends on their ability to respond to the need of the damaged tissue by secreting beneficial paracrine factors. MSCs can be genetically engineered to express certain beneficial factors. The a...

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Bibliographic Details
Main Authors: Jeanne Adiwinata Pawitan, Thuy Anh Bui, Wildan Mubarok, Radiana Dhewayani Antarianto, Retno Wahyu Nurhayati, Ismail Hadisoebroto Dilogo, Delvac Oceandy
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
engineered MSCs
tumor
cancer
metastasis
bone defect
animal models
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2020.587776/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2020.587776/full

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