Deletion of exchange proteins directly activated by cAMP (Epac) causes defects in hippocampal signaling in female mice.

Deletion of exchange proteins directly activated by cAMP (Epac) causes defects in hippocampal signaling in female mice.

Previous studies demonstrate essential roles for the exchange proteins directly activated by cAMP 1 and 2 (Epac1 and Epac2; here collectively referred to as Epac) in the brain. In the hippocampus, Epac contributes to the control of neuronal growth and differentiation and has been implicated in memor...

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Bibliographic Details
Main Authors: Reidun Aesoy, Haruna Muwonge, Kathrine S Asrud, Misbah Sabir, Solveig L Witsoe, Ronja Bjornstad, Reidun K Kopperud, Erling A Hoivik, Stein Ove Doskeland, Marit Bakke
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6062027?pdf=render

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http://europepmc.org/articles/PMC6062027?pdf=render

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