Biospeciation of Potential Vanadium Drugs of Acetylacetonate in the Presence of Proteins

Biospeciation of Potential Vanadium Drugs of Acetylacetonate in the Presence of Proteins

Among vanadium compounds with potential medicinal applications, [VIVO(acac)2] is one of the most promising for its antidiabetic and anticancer activity. In the organism, however, interconversion of the oxidation state to +III and +V and binding to proteins are possible. In this report, the transform...

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Bibliographic Details
Main Authors: Giuseppe Sciortino, Valeria Ugone, Daniele Sanna, Giuseppe Lubinu, Simone Ruggiu, Jean-Didier Maréchal, Eugenio Garribba
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Chemistry
Subjects:
metal drugs
vanadium
anticancer action
antidiabetic action
proteins
transport in the organism
Online Access:https://www.frontiersin.org/article/10.3389/fchem.2020.00345/full

Internet

https://www.frontiersin.org/article/10.3389/fchem.2020.00345/full

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