B-1a B cells regulate T cell differentiation associated with pregnancy disturbances

During pregnancy, the maternal immune system faces a double dilemma: tolerate the growing semi-allogeneic fetus and at the same time protect the mother and the progeny against pathogens. This requires a fine and extremely regulated equilibrium between immune activation and tolerance. As professional...

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Bibliographic Details
Main Authors: Damian Oscar Muzzio, Rocío eSoldati, Luise eRolle, Marek eZygmunt, Ana Claudia Zenclussen, Federico eJensen
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-01-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00006/full