MCM7 Knockdown Inhibits Migration and Invasion While Induces Apoptosis of Cutaneous Malignant Melanoma Cells Through AKT Signaling Pathway

MCM7 Knockdown Inhibits Migration and Invasion While Induces Apoptosis of Cutaneous Malignant Melanoma Cells Through AKT Signaling Pathway

Objective To investigate the functional impact of minichromosome maintenance protein 7 (MCM7) silencing on cutaneous malignant melanoma (CMM) cell apoptosis and proliferation via AKT signaling pathway. Methods Lentivirus vector (LV)-shRNA-MCM7 was constructed, and A375 cells were assigned into contr...

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Bibliographic Details
Main Authors: TANG Hua, FENG Hao, XIAO Weirong, LIAO Yangying, LI Lan, XU Xiaopeng, YAN Xiaohan
Format: Article
Language:zho
Published: Magazine House of Cancer Research on Prevention and Treatment 2018-10-01
Series:Zhongliu Fangzhi Yanjiu
Subjects:
minichromosome maintenance protein 7
akt signaling pathway
melanoma
cells apoptosis
Online Access:http://html.rhhz.net/ZLFZYJ/html/8578.2018.18.0318.htm

Internet

http://html.rhhz.net/ZLFZYJ/html/8578.2018.18.0318.htm

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