Ensemble Modeling of Cancer Metabolism

The metabolic behaviour of cancer cells is adapted to meet their proliferative needs, with notable changes such as enhanced lactate secretion and glucose uptake rates. In this work, we use the Ensemble Modeling (EM) framework to gain insight and predict potential drug targets for tumour cells. EM ge...

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Bibliographic Details
Main Authors: Tahmineh eKhazaei, Alison P McGuigan, Radhakrishnan eMahadevan
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-05-01
Series:Frontiers in Physiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2012.00135/full