Antisense oligonucleotides directed against insulin-like growth factor-II messenger ribonucleic acids delay the progress of rat hepatocarcinogenesis

Antisense oligonucleotides directed against insulin-like growth factor-II messenger ribonucleic acids delay the progress of rat hepatocarcinogenesis

Background: Hepatocellular carcinoma (HCC) is a multistep complex process, caused by many of genetic alteration. Insulin-like growth factors and their receptor have been widely implicated to HCC. Insulin-like growth factor-II (IGF-II) is a mitogenic polypeptide, found in various fetal and neonatal t...

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Bibliographic Details
Main Authors: Miltu Kumar Ghosh, Falguni Patra, Shampa Ghosh, Chowdhury Mobaswar Hossain, Biswajit Mukherjee
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2014-01-01
Series:Journal of Carcinogenesis
Subjects:
Antisense oligonucleotides
hepatic altered foci
hepatocellular carcinoma
hyperplastic nodules
insulin-like growth factor
Online Access:http://www.carcinogenesis.com/article.asp?issn=1477-3163;year=2014;volume=13;issue=1;spage=2;epage=2;aulast=Ghosh

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http://www.carcinogenesis.com/article.asp?issn=1477-3163;year=2014;volume=13;issue=1;spage=2;epage=2;aulast=Ghosh

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